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KMID : 0380319880410000117
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Journal of Korean Research Institute for Better Living
1988 Volume.41 No. 0 p.117 ~ p.124
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Immunocytochemical observation of the gastrin cell in the pyloric antrum of the fetal and neonatal rats
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Abstract
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The structure and distribution of gastrin cells in the gastrointestinal tract of albino rats, Sprague-Dawley strain, have been clarified, but little have been studied on the ontogeny of the gastrin cells.
The present study was attempted to examine the gastrin-immunoreactive cells in the pyloric antrum of the fetal and neonatal rats.
In the 19-day-old fetuses the gastrin cells were identified in the epithelium of the pyloric antrum with the glands. In the early period of neonate the gastrin cells were gradually increased and most of the cells were located in the base of the pyloric gland. It imply that the gastrin cell may influence the gastric mucosal cellular proliferative activity during various stages of late fetal and early neonatal development.
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